The Jacksonville Jaguars secured a dramatic 26 to 21 road win over the San Francisco 49ers on September 28, 2025, in Week 4 of the NFL regular season. The game at Levi’s Stadium in Santa Clara featured intense battles on both offense and defense, along with pivotal special teams plays. The final result surprised many fans and analysts as the Jaguars overcame a formidable 49ers squad.

This detailed article covers the final score, team and player stats, key moments, and what this game means for both teams’ seasons. It is designed for fans, analysts, and anyone looking for a comprehensive and data-rich summary.

Match Summary

The Jacksonville Jaguars defeated the San Francisco 49ers 26 to 21. The Jaguars improved their record to 3-1 while the 49ers fell to 3-1. Despite the 49ers gaining more total yardage, the Jaguars capitalized on turnovers and crucial plays to secure the win. The ability to convert opportunities into points was the defining factor.

Team Statistics

Even though the 49ers outgained Jacksonville in total yards, the Jaguars were opportunistic and efficient. Four turnovers forced by the Jaguars led directly to scoring opportunities and shifted momentum throughout the game.

Jacksonville Jaguars Player Stats

Trevor Lawrence – Quarterback

• 21 completions on 31 attempts
• 174 passing yards
• 1 touchdown
• 0 interceptions

Lawrence managed the game effectively, protecting the football and delivering key completions, including a touchdown that helped establish an early lead.

Travis Etienne Jr. – Running Back

• 19 carries for 124 rushing yards
• 1 rushing touchdown (48 yards)

Etienne provided explosive plays on the ground, consistently picking up critical yardage and scoring the Jaguars’ second offensive touchdown.

Brian Thomas Jr. – Wide Receiver

• 5 receptions for 49 yards

Thomas was Jacksonville’s top receiving option, contributing in a game where the passing attack was balanced and methodical.

Defense and Special Teams

• Parker Washington returned a punt 87 yards for a touchdown
• Devin Lloyd recorded multiple defensive takeaways
• Arik Armstead recorded a game-sealing strip sack

These defensive and special teams plays were decisive, providing both scoring momentum and late-game security.

San Francisco 49ers Player Stats

Brock Purdy – Quarterback

• 22 completions on 38 attempts
• 309 passing yards
• 2 touchdowns
• 2 interceptions

Purdy had strong yardage totals but his interceptions at critical moments negatively affected field position and momentum.

Christian McCaffrey – Running Back

• 17 carries for 49 rushing yards
• 6 receptions for 92 receiving yards
• 1 receiving touchdown

McCaffrey remained the 49ers’ most versatile offensive weapon, generating significant yardage both on the ground and through the air.

Additional Contributors

• Jake Tonges recorded a touchdown reception in the second half

Although the 49ers scored late, the Jaguars’ defense responded effectively to preserve the lead.

Key Moments and Game Turning Points

Turnovers

Jacksonville forced four turnovers, each leading to scoring opportunities. This played a major role in determining the outcome of the game and offset the 49ers’ yardage advantage.

Special Teams

Parker Washington’s 87-yard punt return for a touchdown was a pivotal play that shifted momentum. It was the Jaguars’ first punt return touchdown in several seasons and energized the team.

Defensive Plays

A strip-sack by Arik Armstead late in the game allowed Foyesade Oluokun to recover the fumble, sealing the Jaguars’ victory as the 49ers attempted a comeback.

Game Narrative

Trevor Lawrence highlighted the team’s resilience and leadership, emphasizing the collective effort in a closely contested game.

Advanced Stats and Analysis

Time of Possession

Jacksonville controlled the clock for 32 minutes and 31 seconds, keeping the defense rested and allowing the offense to maintain rhythm in crucial situations.

Penalties

Despite accruing 90 penalty yards, the Jaguars overcame discipline issues, demonstrating focus and resilience under pressure.

Yardage vs Outcome

The 49ers gained more total yards and first downs than the Jaguars, but Jacksonville’s efficiency in turnovers and special teams plays ensured their victory. This highlights that total yardage alone does not determine the outcome of a game.

Historical Context

Historically, the Jaguars have struggled on the West Coast, making this road win particularly significant. It marked a rare victory in California, showing the growth and development of the team under coach Liam Coen. This game also provides useful data for analyzing trends in player performance and team strategy.

Conclusion

The Jacksonville Jaguars’ 26 to 21 win over the San Francisco 49ers showcased opportunistic defense, clutch special teams, and timely offensive execution. Key performances by Trevor Lawrence, Travis Etienne Jr., and pivotal defensive plays were critical to the win. This game is a defining moment of Week 4 in the 2025 NFL season and provides rich material for analysis, fantasy insights, and statistical summaries.

The outcome demonstrates that a team can win even when outgained in yardage if turnovers and special teams are leveraged effectively. For fans and analysts, this game offers key lessons in strategy, execution, and the importance of momentum-changing plays.

Frequently Asked Questions (FAQs)

Q: Where can I find the full Jacksonville Jaguars vs 49ERS Match Player Stats for Sep 28, 2025?

A: The full Jacksonville Jaguars vs 49ERS Match Player Stats include passing, rushing, receiving, and defensive stats for every key player. Trevor Lawrence led the Jaguars in passing, Travis Etienne Jr. had a breakout rushing game, and Parker Washington scored a punt return touchdown. These stats help fans analyze player performance and game impact.

Q: Who were the standout players in the Jaguars vs 49ers game on September 28, 2025?

A: Key players included Trevor Lawrence, Travis Etienne Jr., and Brian Thomas Jr. for the Jaguars, and Brock Purdy and Christian McCaffrey for the 49ers. Defensive players like Devin Lloyd and Arik Armstead made game-changing plays that influenced the final outcome.

Q: What was the final score of the Jaguars vs 49ers match on September 28, 2025?

A: The Jacksonville Jaguars defeated the San Francisco 49ers 26 to 21. Turnovers and special teams were critical in shaping this closely contested victory.

Q: How did turnovers and special teams affect the outcome of the Jaguars vs 49ers game?

A: Jacksonville forced four turnovers, which led to scoring opportunities and crucial momentum swings. Parker Washington’s 87-yard punt return touchdown was a pivotal special teams play that helped the Jaguars secure their win.

Q: How can the Jaguars vs 49ers stats help fantasy football analysis?

A: Player stats, including passing yards, rushing yards, receiving yards, and touchdowns, are essential for fantasy football scoring. Knowing which players had breakout performances, such as Travis Etienne Jr. and Christian McCaffrey, allows fantasy managers to make informed decisions for their lineups.